Can I use Ginkgo biloba and Health Evolution formulas if I have certain health issues?

We provide premium dietary supplements designed to enhance health and wellness. In many parts of the world, it is illegal to make medical claims for foods and alternative therapies even when there are clinically proven benefits. For this reason, we do not make any medical claims for our products, which are not designed to treat, cure, prevent or diagnose disease. 

In this as in all things in life, you should carry out your own research and make your own decisions. 

One of the questions we are asked the most is about Ginkgo biloba, one of the active ingredients in AminoBoosters and TeloMind.

Ginkgo biloba is a herb that has been used for the longest time. In fact, recorded evidence of its use to treat bronchitis, asthma, and other conditions dates back almost five thousand years!

Gingko biloba is not suitable for people using warfarin or other blood-thinning medication. This is because it has blood-thinning properties and therefore should not be used if you are taking anticoagulant (blood-thinning) medications, such as aspirin, clopidogrel (Plavix), dipyridamole (Persantine), heparin, ticlopidine (Ticlid), or warfarin (Coumadin).

Accumulating evidence suggests that Ginkgo biloba is cardioprotective, in part through its vasodilatory and antihypertensive properties. However, definitive data on its blood pressure-lowering effects in humans is lacking. See and other studies.

Ginkgo is actually a large tree that grows natively in China, Japan, and Korea natively and has been cultivated in Europe and North America since the mid-1700s. We actually have a young Ginkgo tree growing on our Australian estate. It’s one of the oldest tree species still in existence, and it is one of the longest-lived, with a general lifespan of over a thousand years.

Typically, the leaves are used to create the supplement ingredient.

We use the highest quality Ginkgo biloba leaf extract in our AminoBoosters and TeloMind formulas.

Ginko is most commonly used to treat memory disorders that stem from inadequate blood flow to the brain, especially in older patients, inclding people with Alzheimer’s. Other conditions it is used to help include:

  • Dizziness
  • Mood swings and changes
  • Difficulty concentrating
  • Claudication – leg pain during walking due to low blood flow

There is a very long list of other ailments Ginkgo biloba can treat, since the herb has been used for so many thousands of years.

Other conditions it’s been successful at treating or improving include:

  • Reduced levels of anxiety
  • Some improved symptoms of dementia-related to vascular disease and Alzheimer’s
  • Improvement of color vision in diabetic patients with retinal damage
  • Improvement in the visual field of glaucoma patients (with long term use)
  • Relief of breast tenderness and other symptoms of PMS
  • Reduction of symptoms of schizophrenia, when paired with antipsychotics
  • Improvement in symptoms of vertigo and other balance disorders
  • Preliminary work has suggested Ginkgo biloba may help with MS-associated cognitive problems.

How gingko biloba works

Ginkgo biloba has several properties that are perhaps the reason it is so efficient at treating a number of ailments. Promoting blood flow and circulation is one of the biggest factors, which is what may help with brain function, as well as improved senses. Additional benefits of gingko biloba include:

  • Antioxidant properties, which slow down the progression of Alzheimer’s, as well as assist in improved cognition and thinking ability.
  • Antibacterial and antifungal properties, which can help reduce the chances of infection or even kill infection in the body.

Whenever making changes to your diet and lifestyle, it is recommended to consult with and follow the advice of your professional health adviser.

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Brochet, B., Guinot, P., Orgogozo, J. M., Confavreux, C., Rumbach, L., and Lavergne, V. Double blind placebo controlled multicentre study of ginkgolide B in treatment of acute exacerbations of multiple sclerosis. The Ginkgolide Study Group in multiple sclerosis. J Neurol Neurosurg Psychiatry 1995;58(3):360-362. View abstract.

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Choi, W. S., Choi, C. J., Kim, K. S., Lee, J. H., Song, C. H., Chung, J. H., Ock, S. M., Lee, J. B., and Kim, C. M. To compare the efficacy and safety of nifedipine sustained release with Ginkgo biloba extract to treat patients with primary Raynaud's phenomenon in South Korea; Korean Raynaud study (KOARA study). Clin Rheumatol. 2009;28(5):553-559. View abstract.

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D'Andrea, G., Bussone, G., Allais, G., Aguggia, M., D'Onofrio, F., Maggio, M., Moschiano, F., Saracco, M. G., Terzi, M. G., Petretta, V., and Benedetto, C. Efficacy of Ginkgolide B in the prophylaxis of migraine with aura. Neurol.Sci 2009;30 Suppl 1:S121-S124. View abstract.

Dardano, A., Ballardin, M., Caraccio, N., Boni, G., Traino, C., Mariani, G., Ferdeghini, M., Barale, R., and Monzani, F. The effect of Ginkgo biloba extract on genotoxic damage in patients with differentiated thyroid carcinoma receiving thyroid remnant ablation with iodine-131. Thyroid 2012;22(3):318-324. View abstract.

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Fan, L., Tao, G. Y., Wang, G., Chen, Y., Zhang, W., He, Y. J., Li, Q., Lei, H. P., Jiang, F., Hu, D. L., Huang, Y. F., and Zhou, H. H. Effects of Ginkgo biloba extract ingestion on the pharmacokinetics of talinolol in healthy Chinese volunteers. Ann Pharmacother. 2009;43(5):944-949. View abstract.

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Guillon, J. M., Rochette, L., and Baranes, J. [Effects of Ginkgo biloba extract on 2 models of experimental myocardial ischemia]. Presse Med 9-25-1986;15(31):1516-1519. View abstract.

Han, S. S., Nam, E. C., Won, J. Y., Lee, K. U., Chun, W., Choi, H. K., and Levine, R. A. Clonazepam quiets tinnitus: a randomised crossover study with Ginkgo biloba. J Neurol.Neurosurg.Psychiatry 2012;83(8):821-827. View abstract.

Hao, Y., Sun, Y., Xu, C., Jiang, X., Sun, H., Wu, Q., Yan, C., and Gu, S. Improvement of contractile function in isolated cardiomyocytes from ischemia-reperfusion rats by ginkgolide B pretreatment. J Cardiovasc.Pharmacol 2009;54(1):3-9. View abstract.

Hauns, B., Haring, B., Kohler, S., Mross, K., Robben-Bathe, P., and Unger, C. Phase II study with 5-fluorouracil and ginkgo biloba extract (GBE 761 ONC) in patients with pancreatic cancer. Arzneimittelforschung 1999;49(12):1030-1034. View abstract.

He, M., Zhang, X. M., and Yuan, H. Q. [Clinical study on treatment of pulmonary interstitial fibrosis with ginkgo extract]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2005;25(3):222-224. View abstract.

Herrschaft, H., Nacu, A., Likhachev, S., Sholomov, I., Hoerr, R., and Schlaefke, S. Ginkgo biloba extract EGb 761(R) in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg. J Psychiatr.Res 2012;46(6):716-723. View abstract.

Ito, T. Y., Trant, A. S., and Polan, M. L. A double-blind placebo-controlled study of ArginMax, a nutritional supplement for enhancement of female sexual function. J Sex Marital Ther 2001;27(5):541-549. View abstract.

Janssen, I. M., Sturtz, S., Skipka, G., Zentner, A., Velasco, Garrido M., and Busse, R. Ginkgo biloba in Alzheimer's disease: a systematic review. Wien.Med Wochenschr. 2010;160(21-22):539-546. View abstract.

Janssens, D., Michiels, C., Delaive, E., Eliaers, F., Drieu, K., and Remacle, J. Protection of hypoxia-induced ATP decrease in endothelial cells by ginkgo biloba extract and bilobalide. Biochem Pharmacol 9-28-1995;50(7):991-999. View abstract.

Jiang, W., Qiu, W., Wang, Y., Cong, Q., Edwards, D., Ye, B., and Xu, C. Ginkgo may prevent genetic-associated ovarian cancer risk: multiple biomarkers and anticancer pathways induced by ginkgolide B in BRCA1-mutant ovarian epithelial cells. Eur J Cancer Prev. 2011;20(6):508-517. View abstract.

Kampman, K., Majewska, M. D., Tourian, K., Dackis, C., Cornish, J., Poole, S., and O'Brien, C. A pilot trial of piracetam and ginkgo biloba for the treatment of cocaine dependence. Addict.Behav 2003;28(3):437-448. View abstract.

Kaschel, R. Ginkgo biloba: specificity of neuropsychological improvement--a selective review in search of differential effects. Hum.Psychopharmacol. 2009;24(5):345-370. View abstract.

Kaschel, R. Specific memory effects of Ginkgo biloba extract EGb 761 in middle-aged healthy volunteers. Phytomedicine 11-15-2011;18(14):1202-1207. View abstract.

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Kim, T. E., Kim, B. H., Kim, J., Kim, K. P., Yi, S., Shin, H. S., Lee, Y. O., Lee, K. H., Shin, S. G., Jang, I. J., and Yu, K. S. Comparison of the pharmacokinetics of ticlopidine between administration of a combined fixed-dose tablet formulation of ticlopidine 250 mg/ginkgo extract 80 mg, and concomitant administration of ticlopidine 250-mg and ginkgo extract 80-mg tablets: an open-label, two-treatment, single-dose, randomized-sequence crossover study in healthy Korean male volunteers. Clin Ther 2009;31(10):2249-2257. View abstract.

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Di Franco R, Sammarco E, Calvanese MG, De Natale F, Falivene S, Di Lecce A, Giugliano FM, Murino P, Manzo R, Cappabianca S, Muto P, Ravo V. Preventing the acute skin side effects in patients treated with radiotherapy for breast cancer: the use of corneometry in order to evaluate the protective effect of moisturizing creams. Radiat Oncol 2013;8:57. View abstract.

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Guo CX, Pei Q, Yin JY, Peng XD, Zhou BT, Zhao YC, Wu LX, Meng XG, Wang G, Li Q, Ouyang DS, Liu ZQ, Zhang W, Zhou HH. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica 2012;42(8):784-90. View abstract.

Guo X, Kong X, Huang R, Jin L, Ding X, He M, Liu X, Patel MC, Congdon NG. Effect of Ginkgo biloba on visual field and contrast sensitivity in Chinese patients with normal tension glaucoma: a randomized, crossover clinical trial. Invest Ophthalmol Vis Sci 2014;55(1):110-6. View abstract.

Gurley BJ, Gardner SF, Hubbard MA, et al. Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans. Clin Pharmacol Ther 2002;72:276-87.. View abstract.

Gurley BJ, Gardner SF, Hubbard MA. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. AAPS Ann Mtg & Expo Indianapolis, IN: 2000; Oct 29 - Nov 2:presentation #3460.

Haguenauer JP, Cantenot F, Koskas H, Pierart H. [Treatment of equilibrium disorders with Ginkgo biloba extract. A multicenter, double-blind drug vs. placebo study]. Presse Med 1986;15:1569-72. View abstract.

Hartley, D. E., Elsabagh, S., and File, S. E. Gincosan (a combination of Ginkgo biloba and Panax ginseng): the effects on mood and cognition of 6 and 12 weeks' treatment in post-menopausal women. Nutr.Neurosci. 2004;7(5-6):325-333. View abstract.

Hasanzadeh E, Mohammadi MR, Ghanizadeh A, Rezazadeh SA, Tabrizi M, Rezaei F, Akhondzadeh S. A double-blind placebo controlled trial of Ginkgo biloba added to risperidone in patients with autistic disorders. Child Psychiatry Hum Dev 2012;43(5):674-82. View abstract.

Hauns B, Haring B, Kohler S, et al. Phase II study of combined 5-fluorouracil/ Ginkgo biloba extract (GBE 761 ONC) therapy in 5-fluorouracil pretreated patients with advanced colorectal cancer. Phytother Res 2001;15:34-38.. View abstract.

Hauser D, Gayowski T, Singh N. Bleeding complications precipitated by unrecognized Gingko biloba use after liver transplantation. Transpl Int 2002;15:377-9. View abstract.

Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. View abstract.

Hofferberth B. The efficacy of Egb 761 in patients with senile dementia of the Alzheimer type, A double-blind, placebo-controlled study on different levels of investigation. Human Psychopharmacol 1994;9:215-22.

Holgers KM, Axelsson A, Pringle I. Ginkgo biloba extract for the treatment of tinnitus. Audiol 1994;33:85-92. View abstract.

Hopfenmuller W. [Evidence for a therapeutic effect of Ginkgo biloba special extract. Meta-analysis of 11 clinical studies in patients with cerebrovascular insufficiency in old age]. Arzneimittelforschung 1994;44:1005-13. View abstract.

Ihl R, Tribanek M, Bachinskaya N. Baseline neuropsychiatric symptoms are effect modifiers in Ginkgo biloba extract (EGb 761) treatment of dementia with neuropsychiatric features. Retrospective data analyses of a randomized controlled trial. J Neurol Sci 2010;299:184-7. View abstract.

Ihl R, Tribanek M, Bachinskaya N; GOTADAY Study Group. Efficacy and tolerability of a once daily formulation of Ginkgo biloba extract EGb761 in Alzheimer's disease and vascular dementia: results from a randomised controlled trial. Pharmacopsychiatry 2012;45:41-6. View abstract.

Itil TM, Eralp E, Ahmed I, Kunitz A, et al. The pharmacological effects of ginkgo biloba, a plant extract, on the brain of dementia patients in comparison with tacrine. Psychopharmacol Bull 1998;34:391-7. View abstract.

Jiang X, Blair EY, McLachlan AJ. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006;46:1370-8. View abstract.

Jiang X, Williams KM, Liauw WS, et al. Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2005;59:425-32. View abstract.

Kajiyama Y, Fujii K, Takeuchi H, Manabe Y. Ginkgo seed poisoning. Pediatrics 2002;109:325-7. View abstract.

Kang BJ, Lee SJ, Kim MD, Cho MJ. A placebo-controlled, double-blind trial of Ginkgo biloba for antidepressant-induced sexual dysfunction. Hum Psychopharmacol 2002;17:279-84. View abstract.

Kanowski S, Herrmann WM, Stephan K, et al. Proof of efficacy of the ginkgo biloba special extract (EGb 761) in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry 1996;29:47-56. View abstract.

Kellermann AJ, Kloft C. Is there a risk of bleeding associated with standardized ginkgo biloba extract therapy? A systematic review and meta-analysis. Pharmacotherapy 2011;31:490-502. View abstract.

Kennedy DO, Scholey AB, Wesnes KA. The dose-dependent cognitive effects of acute administration of Ginkgo biloba to healthy young volunteers. Psychopharmacology (Berl) 2000;151:416-23. View abstract.

Kim BH, Kim KP, Lim KS, et al. Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: An open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers. Clin Ther 2010;32:380-90. View abstract.

Kleijnen J, Knipschild P. Ginkgo biloba for cerebral insufficiency. Br J Clin Pharmacol 1992;34:352-8. View abstract.

Kohler S, Funk P, Kieser M. Influence of a 7-day treatment with Ginkgo biloba special extract EGb 761 on bleeding time and coagulation: a randomized, placebo-controlled, double-blind study in healthy volunteers. Blood Coagul Fibrinolysis 2004;15:303–9. View abstract.

Kressmann S, Muller WE, Blume HH. Pharmaceutical quality of different Ginkgo biloba brands. J Pharm Pharmacol 2002;54:661-9. View abstract.

Kudolo G. Ingestion of Ginkgo biloba extract significantly inhibits collagen-induced platelet aggregation and thromboxane A2 synthesis. Alt Ther 2001;7:105.

Kudolo GB, Delaney D, Blodgett J. Short-term oral ingestion of Ginkgo biloba extract (EGb 761) reduces malondialdehyde levels in washed platelets of type 2 diabetic subjects. Diabetes Res Clin Pract 2005;68:29-38. View abstract.

Kudolo GB, Dorsey S, Blodgett J. Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. Thromb Res 2002;108:151-60.. View abstract.

Kudolo GB, Wang W, Elrod R, et al. Short-term ingestion of Ginkgo biloba extract does not alter whole body insulin sensitivity in non-diabetic, pre-diabetic or type 2 diabetic subjects--a randomized double-blind placebo-controlled crossover study. Clin Nutr 2006;25:123-34. View abstract.

Kudolo GB, Wang W, Javors M, Blodgett J. The effect of the ingestion of Ginkgo biloba extract (EGb 761) on the pharmacokinetics of metformin in non-diabetic and type 2 diabetic subjects-A double blind placebo-controlled, crossover study. Clin Nutr 2006;25:606-16. View abstract.

Kudolo GB. The effect of 3-month ingestion of Ginkgo biloba extract on pancreatic beta-cell function in response to glucose loading in normal glucose tolerant individuals. J Clin Pharmacol 2000;40:647-54. View abstract.

Kudolo GB. The effect of 3-month ingestion of Ginkgo biloba extract (EGb 761) on pancreatic beta-cell function in response to glucose loading in individuals with non-insulin-dependent diabetes mellitus. J Clin Pharmacol 2001;41:600-11. View abstract.

Kuller LH, Ives DG, Fitzpatrick AL, et al. Does Ginkgo biloba reduce the risk of cardiovascular events? Circ Cardiovasc Qual Outcomes 2010;3:41-7. View abstract.

Kupiec T, Raj V. Fatal seizures due to potential herb-drug interactions with Ginkgo biloba. J Anal Toxicol 2005:755-8. View abstract.

Kurz A, Van Baelen B. Ginkgo biloba compared with cholinesterase inhibitors in the treatment of dementia: a review based on meta-analyses by the Cochrane collaboration. Dement Geriatr Cogn Disord 2004;18:217-26. View abstract.

Lai SW, Chen JH, Kao WY. Acute hemolytic anemia in glucose-6-phosphate dehydrogenase deficiency complicated by Ginkgo biloba. Acta Haematol 2013;130(4):288-90. View abstract.

Lanthony P, Cosson JP. [The course of color vision in early diabetic retinopathy treated with ginkgo biloba extract. A preliminary, double-blind versus placebo study]. J Fr Ophtalmol 1988;11:671-4. View abstract.

Le Bars PL, Katz MM, Berman N, et al. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA 1997;278:1327-32. View abstract.

Le Bars PL, Kieser M, Itil KZ. A 26-week analysis of a double-blind, placebo-controlled trial of the Ginkgo biloba extract EGb 761 in dementia. Dement Geriatr Cogn Disord 2000;11:230-7. View abstract.

Lebuisson DA, Leroy L, Rigal G. [Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind drug vs. placebo study]. (Abstract). Presse Med 1986;15:1556-8. View abstract.

Levine SB. Caution recommended. J Sex Marital Ther 1999;25:2-5. View abstract.

Li AL, Shi YD, Landsmann B, et al. Hemorheology and walking of peripheral arterial occlusive diseases patients during treatment with Ginkgo biloba extract. Chung Kuo Yao Li Hsueh Pao 1998;19:417-21. View abstract.

Li W, Fitzloff JF, Farnsworth NR, Fong HH. Evaluation of commercial Ginkgo biloba dietary supplements for the presence of colchicine by high-performance liquid chromatography. Phytomedicine 2002;9:442-6. View abstract.


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It is not permitted to make health claims for dietary supplements in many parts of the world. This reminds us of Einstein's famous quotation, "Coincidence is God's way of remaining anonymous". What we can say is that our products are specifically formulated to:

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